Disc Medicine received an FDA Complete Response Letter for bitopertin, targeting erythropoietic protoporphyria (EPP). Despite showing PPIX reduction, trials lacked proof of clear clinical benefits, delaying approval and causing stock fluctuation.
Older homeowners selling after 70s may get 5% less, facing $20K+ cuts due to deferred maintenance & late decisions. With a buyer-leaning market and new housing legislation, seniors' large home equity is at risk, highlighting the need for early planning.
A DHS funding gap forces TSA officers to work without pay, raising concerns over staffing shortages and flight delays. Experts advise travelers to arrive early and show patience as the shutdown impacts airport operations.
Taiwan and the US agree to cut tariffs on exports while negotiating the relocation of semiconductor supply chains amid rising geopolitical tensions and surging AI-driven chip demand.
EU-Turkey trade hit EUR210B in 2024, yet EU membership talks remain stalled due to Turkey's democratic backsliding and Hamas support. Security cooperation, especially concerning drones and Russian threats, intensifies, driven by EU's strategic interests and Turkey's crucial location. The relationship remains largely transactional.
A Boston College report highlights the need for fraud prevention in private businesses. The 'fake it till you make it' culture fosters white-collar crimes in startups, exemplified by Elizabeth Holmes. Forbes' 30 Under 30 list has seen honorees embroiled in financial fraud scandals.
The Trump administration is increasing humanitarian aid to Cuba by $6 million via the Catholic Church and Caritas due to a crisis exacerbated by Typhoon Melissa and stopped Venezuelan oil shipments. Cuban President Díaz-Canel expresses willingness for dialogue with the U.S. without pressure.
Waymo raised $16B in funding, valuing the robotaxi leader at $126B, signaling strong investor confidence in autonomous vehicle services. The company plans to expand its fleet and operations into over 20 new global cities by 2026.
The EU & India finalized a major FTA, reducing tariffs on over 96% of goods. This "mother of all trade deals" links 2B consumers, potentially boosting EU exports by 6.4% & supporting de-risking from China, despite US tensions.
Prediction markets like Kalshi & Polymarket now offer contracts on Super Bowl 60 ads, raising insider trading concerns. Employees privy to ad plans could leverage info, posing regulatory challenges in this new online trading frontier.
Deep-pocketed investors show a bearish stance on Applied Materials (AMAT) with unusual options activity. As a semiconductor giant, these significant trades hint at potential major moves in the electronic market.
President Trump declared a national emergency over Cuba via executive order, citing the communist regime's alignment with hostile foreign powers and terrorist groups. The order mandates tariffs on countries supplying oil to Cuba and aims to oust Cuba's Communist management, believing its economy is near collapse after losing Venezuelan aid.
John Deere is expanding with a new Kernersville excavator plant and an Indiana warehouse, shifting production from Japan. Amidst Trump's farm aid and price warnings, Deere faces average market performance and a worse-than-expected 2026 financial outlook with a $1.2B toll hit.
UnitedHealth Group (UNH) is facing elevated medical costs impacting margins, with investors focused on Q4 results and future positioning. A low 0.09% Medicare Advantage rate boost for 2027 adds pressure, contrasting with higher industry and company cost projections.
Winter Storm Brush causes widespread US disruptions, affecting energy production and power grids (PJM, CenterPoint, Duke Energy, Exelon) with potential stock changes. It also prompts massive flight cancellations (Delta, JetBlue, United), with forecasts of heavy snow and power blackouts.
US natural gas prices surged 60% weekly, hitting $5/MMBtu, driven by a record cold wave expected in 40 states. This boosted energy equities like Antero Resources and EQT, as forecasts warn of heavy snow and strained power systems, anticipating record withdrawals.
Discussion on CAFE standards relaxation, impacting automakers like Tesla, Ford, GM and Stellantis. Concerns raised over affordability, safety, and competition with China in EVs and clean energy. Impact on vehicle costs and innovation debated.
